Phosphate Balance and CKD–Mineral Bone Disease

Protecting calcium and phosphate balance in chronic renal disease.

I n its earliest stages, chronic kidney disease (CKD) is associated with a failure to regulate phosphate balance optimally. Multiple aspects of normal renal physiology—from maintenance of an adequate GFR to responsiveness of the nephron to systemic and local signals that regulate phosphate secretion—underlie the deterioration in phosphate control as CKD progresses. The human organism is endowed...

Monogenic Phosphate Balance Disorders

Pilates Exercise and Functional Balance in Parkinson\'s Disease

Background: Parkinson's disease as a progressive disorder of the nervous system leads to the disability of postural control system. Objectives: In the present study the effects of Pilates exercises on functional balance in patients with Parkinson's was investigated. Materials and Methods: This control trial included 30 patients with idiopathic Parkinson's disease who were selected as subj...

Histomorphometric Analysis of Newly-formed Bone Using Octacalcium Phosphate and Bone Matrix Gelatin in Rat Tibial Defects

Background: Repair of bone defects is challenging for reconstructive and orthopedic surgeons. In this study, we aimedto histomorphometrically assess new bone formation in tibial bone defects filled with octacalcium phosphate (OCP),bone matrix gelatin (BMG), and a combination of both.Methods: A total of 96 male Sprague Dawley rats aged 6-8 weeks weighing 120-150 g were randomly allocatedinto thr...

Celiac Disease, Gluten-Free Diet, and Bone Mass Density

Background: Celiac disease (CD), as an autoimmune disease has initiated since ingestion of food containing gluten. Constant intolerance to gluten causes damages of the small intestinal mucosa. One reason of mal-absorption in children and infants is CD. Additionally, about 75% of newly identified patients with CD have low bone mineral density (BMD). Many factors have role in metabolic bone disea...